HLA B-2+7 HLA B27 Positive Ayurvedic Treatment

HLA B-2+7 HLA B27 Positive Ayurvedic TreatmentWhat is HLA-B27 blood test?
HLA-B27 test is a blood test to diagnoseHLA-B27 gene. This gene predisposes to a number of autoimmune diseases including , Reactive arthritis & uveitis.
When is HLA-B27 test ordered?
Your orthopedic doctor will order HLA-B27 test if he suspects Ankylosing spondylitis, reactive arthritis. The suspicion is raised by inflammatory backache or pain/ swelling in knee/ ankle/ feet joints.
What does a positive HLA-B27 test mean?
A positive test means that the person carries the HLA-b27 gene. One inherits the gene from his/ her parents. This is not a diagnostic test. It does not mean that the person has Ankylosing spondylitis. A negative test does not rule out Ankylosing spondylitis.


A HLA-B27 positive test means that the patients tested is at increased risk of developing certain autoimmune diseases. If the person has symptoms such as chronic pain, inflammation, and/ or degenerative changes to bones ( on X-ray), then it supports a diagnosis of Ankylosing Spondylitis, Reactive Arthritis, or another autoimmune disorder that is related to HLA-B27+. This is especially true if the person is young, male, and if he experienced his first symptoms before the age of 40.

An HLA disease association is defined as a statistically increased frequency of the HLA haplotype in individuals with the disease compared to the frequency in individuals without the disease. This is expressed as a relative risk. For example, HLA-B27 appears in 80-90% of patients with ankylosing spondylitis. Expressed as a relative risk, an HLA-B27 positive individual is approximately 87 times more susceptible to developing ankylosing spondylitis compared to the general population.

HLA-B27 is Associated With Autoimmune Diseases

The prevalence of HLA-B27 varies between ethnic groups and populations worldwide but is generally not a very common haplotype. Only 8 percent of Caucasians, 4 percent of North Africans, 2 to 9 percent of Chinese, and 0.1 to 0.5 percent of Japanese people possess HLA-B27 positive blood test.

Ankylosing Spondylitis (AS) is the most common disease which affect about 85+% of positive persons it is an inflammatory disease in which some of the vertebrae of the spine fuse together, inhibiting mobility. An estimated 88 percent of people with AS are HLA-B27 positive, yet only a fraction of HLA-B27-positive people will develop AS. Other autoimmune diseases that are associated with an HLA-B27 haplotype include Crohn’s disease, ulcerative colitis, psoriasis, reactive arthritis, and uveitis.


HLA-B27 Associated Diseases

  • Acute Anterior Uveitis
  • Ankylosing Spondylitis
  • Reactive Arthritis
  • Associations of Reactive Arthritis with bacterial infection
  • Inflammatory Bowel Disease: Ulcerative Colitis and Crohn’s Disease
  • Psoriasis and Psoratic Arthritis

The most common problem which affect about 88% or HLAB27 positive person is Ankylosing Spondylitis.

Medicine for HLAB27 Positive

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